The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:
"HUPs
".
FunFam 86531: Probable cysteine--tRNA ligase, mitochondrial
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 17 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cysteine-tRNA ligase activity GO:0004817
Catalysis of the reaction: ATP + L-cysteine + tRNA(Cys) = AMP + diphosphate + L-cysteinyl-tRNA(Cys).
|
10 | Q09860 (/ISS) Q291L4 (/ISS) Q4R550 (/ISS) Q54KR1 (/ISS) Q54ZY3 (/ISS) Q5F408 (/ISS) Q5M7N8 (/ISS) Q7KN90 (/ISS) Q7ZWR2 (/ISS) Q9ER72 (/ISS) |
|
TRNA binding GO:0000049
Interacting selectively and non-covalently with transfer RNA.
|
8 | Q291L4 (/ISS) Q4R550 (/ISS) Q54KR1 (/ISS) Q5F408 (/ISS) Q5M7N8 (/ISS) Q7KN90 (/ISS) Q7ZWR2 (/ISS) Q9ER72 (/ISS) |
|
Cysteine-tRNA ligase activity GO:0004817
Catalysis of the reaction: ATP + L-cysteine + tRNA(Cys) = AMP + diphosphate + L-cysteinyl-tRNA(Cys).
|
3 | P49589 (/TAS) Q7K3P0 (/TAS) Q7KN90 (/TAS) |
|
Cysteine-tRNA ligase activity GO:0004817
Catalysis of the reaction: ATP + L-cysteine + tRNA(Cys) = AMP + diphosphate + L-cysteinyl-tRNA(Cys).
|
2 | P49589 (/IDA) P53852 (/IDA) |
|
TRNA binding GO:0000049
Interacting selectively and non-covalently with transfer RNA.
|
1 | P49589 (/IDA) |
|
TRNA binding GO:0000049
Interacting selectively and non-covalently with transfer RNA.
|
1 | P49589 (/IMP) |
|
TRNA binding GO:0000049
Interacting selectively and non-covalently with transfer RNA.
|
1 | Q9ER72 (/ISO) |
|
TRNA binding GO:0000049
Interacting selectively and non-covalently with transfer RNA.
|
1 | P49589 (/NAS) |
|
Cysteine-tRNA ligase activity GO:0004817
Catalysis of the reaction: ATP + L-cysteine + tRNA(Cys) = AMP + diphosphate + L-cysteinyl-tRNA(Cys).
|
1 | Q9ER72 (/ISO) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | P49589 (/IPI) |
|
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
|
1 | P49589 (/IDA) |
|
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
|
1 | Q9ER72 (/ISO) |
|
Cysteine-glucosaminylinositol ligase activity GO:0035446
Catalysis of the reaction: 1-(2-amino-2-deoxy-alpha-D-glucopyranoside)-1D-myo-inositol + L-cysteine + ATP = 1-D-myo-inosityl-2-L-cysteinylamido-2-deoxy-alpha-D-glucopyranoside + AMP + diphosphate + 2 H+. 1-(2-amino-2-deoxy-alpha-D-glucopyranoside)-1D-myo-inositol is also known as glucosaminyl-inositol or GlcN-Ins, and 1-D-myo-inosityl-2-L-cysteinylamido-2-deoxy-alpha-D-glucopyranoside as desacetylmycothiol or Cys-GlcN-Ins.
|
1 | P9WJM9 (/IDA) |
|
Cysteine-glucosaminylinositol ligase activity GO:0035446
Catalysis of the reaction: 1-(2-amino-2-deoxy-alpha-D-glucopyranoside)-1D-myo-inositol + L-cysteine + ATP = 1-D-myo-inosityl-2-L-cysteinylamido-2-deoxy-alpha-D-glucopyranoside + AMP + diphosphate + 2 H+. 1-(2-amino-2-deoxy-alpha-D-glucopyranoside)-1D-myo-inositol is also known as glucosaminyl-inositol or GlcN-Ins, and 1-D-myo-inosityl-2-L-cysteinylamido-2-deoxy-alpha-D-glucopyranoside as desacetylmycothiol or Cys-GlcN-Ins.
|
1 | P9WJM9 (/TAS) |
|
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
1 | P49589 (/IDA) |
|
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
1 | P49589 (/IMP) |
|
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
1 | Q9ER72 (/ISO) |
There are 10 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cysteinyl-tRNA aminoacylation GO:0006423
The process of coupling cysteine to cysteinyl-tRNA, catalyzed by cysteinyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
|
10 | Q09860 (/ISS) Q291L4 (/ISS) Q4R550 (/ISS) Q54KR1 (/ISS) Q54ZY3 (/ISS) Q5F408 (/ISS) Q5M7N8 (/ISS) Q7KN90 (/ISS) Q7ZWR2 (/ISS) Q9ER72 (/ISS) |
|
Cysteinyl-tRNA aminoacylation GO:0006423
The process of coupling cysteine to cysteinyl-tRNA, catalyzed by cysteinyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
|
2 | P49589 (/IDA) P53852 (/IDA) |
|
Cysteinyl-tRNA aminoacylation GO:0006423
The process of coupling cysteine to cysteinyl-tRNA, catalyzed by cysteinyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
|
2 | Q7K3P0 (/TAS) Q7KN90 (/TAS) |
|
Cytoplasmic translation GO:0002181
The chemical reactions and pathways resulting in the formation of a protein in the cytoplasm. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein.
|
1 | Q09860 (/NAS) |
|
TRNA aminoacylation for protein translation GO:0006418
The synthesis of aminoacyl tRNA by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA, to be used in ribosome-mediated polypeptide synthesis.
|
1 | P49589 (/TAS) |
|
Cysteinyl-tRNA aminoacylation GO:0006423
The process of coupling cysteine to cysteinyl-tRNA, catalyzed by cysteinyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
|
1 | Q9ER72 (/ISO) |
|
Spore germination GO:0009847
The physiological and developmental changes that occur in a spore following release from dormancy up to the earliest signs of growth (e.g. emergence from a spore wall).
|
1 | C8V9N8 (/IMP) |
|
Mycothiol biosynthetic process GO:0010125
The chemical reactions and pathways resulting in the formation of mycothiol, which consists of N-acetyl-L-cysteine linked to a pseudodisaccharide, D-glucosamine and myo-inositol. Mycothiol is produced in actinomycetes like mycobacteria and serves similar functions to glutathione.
|
1 | P9WJM9 (/TAS) |
|
Cell growth GO:0016049
The process in which a cell irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present.
|
1 | P9WJM9 (/IMP) |
|
Growth GO:0040007
The increase in size or mass of an entire organism, a part of an organism or a cell.
|
1 | P9WJM9 (/IMP) |
There are 12 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
8 | Q291L4 (/ISS) Q4R550 (/ISS) Q54KR1 (/ISS) Q5F408 (/ISS) Q5M7N8 (/ISS) Q7KN90 (/ISS) Q7ZWR2 (/ISS) Q9ER72 (/ISS) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
5 | A0A024RCG3 (/IDA) B4DKY1 (/IDA) P49589 (/IDA) Q09860 (/IDA) Q8IJP3 (/IDA) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
2 | P49589 (/TAS) P9WJM9 (/TAS) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | P49589 (/IDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q9ER72 (/ISO) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | P49589 (/NAS) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q7KN90 (/TAS) |
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
1 | Q7K3P0 (/TAS) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q9ER72 (/ISO) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | P9WJM9 (/IDA) |
|
Apicoplast GO:0020011
The plastid organelle found in apicomplexans.
|
1 | Q8IJP3 (/IDA) |
|
Phagocytic vesicle GO:0045335
A membrane-bounded intracellular vesicle that arises from the ingestion of particulate material by phagocytosis.
|
1 | Q54KR1 (/IDA) |
