# STOCKHOLM 1.0
#=GF ID 3.40.50.2300/FF/151850
#=GF DE Hydrogenase transcriptional regulatory protein HoxA
#=GF AC 3.40.50.2300/FF/151850
#=GF TP FunFam
#=GF DR CATH: 4.2
#=GF DR DOPS: 82.219
#=GS Q9KT19/1-134       AC Q9KT19
#=GS Q9KT19/1-134       OS Vibrio cholerae O1 biovar El Tor str. N16961
#=GS Q9KT19/1-134       DE Response regulator
#=GS Q9KT19/1-134       DR GENE3D; 1c930dca0238f6dbba51cf23a88cafa5/1-134; 
#=GS Q9KT19/1-134       DR ORG; Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae; Vibrio; Vibrio cholerae; 
#=GS Q9KT19/1-134       DR GO; GO:0000156; GO:0000160; 
#=GS P31908/5-138       AC P31908
#=GS P31908/5-138       OS Bradyrhizobium diazoefficiens USDA 110
#=GS P31908/5-138       DE Hydrogenase transcriptional regulatory protein HoxA
#=GS P31908/5-138       DR GENE3D; f8ffddd9c8d0a5044165741a0ea36ad6/5-138; 
#=GS P31908/5-138       DR ORG; Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales; Bradyrhizobiaceae; Bradyrhizobium; Bradyrhizobium diazoefficiens; 
#=GS A0A0K9UTJ2/1-134   AC A0A0K9UTJ2
#=GS A0A0K9UTJ2/1-134   OS Vibrio cholerae 2740-80
#=GS A0A0K9UTJ2/1-134   DE Diguanylate cyclase
#=GS A0A0K9UTJ2/1-134   DR GENE3D; 1c930dca0238f6dbba51cf23a88cafa5/1-134; 
#=GS A0A0K9UTJ2/1-134   DR ORG; Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae; Vibrio; Vibrio cholerae; 
#=GS A0A0H6KNA5/1-134   AC A0A0H6KNA5
#=GS A0A0H6KNA5/1-134   OS Vibrio cholerae
#=GS A0A0H6KNA5/1-134   DE Diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(S)
#=GS A0A0H6KNA5/1-134   DR GENE3D; 1c930dca0238f6dbba51cf23a88cafa5/1-134; 
#=GS A0A0H6KNA5/1-134   DR ORG; Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae; Vibrio; Vibrio cholerae; 
#=GS A0A0H3PX26/1-134   AC A0A0H3PX26
#=GS A0A0H3PX26/1-134   OS Vibrio cholerae B33
#=GS A0A0H3PX26/1-134   DE Diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(S)
#=GS A0A0H3PX26/1-134   DR GENE3D; 1c930dca0238f6dbba51cf23a88cafa5/1-134; 
#=GS A0A0H3PX26/1-134   DR ORG; Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae; Vibrio; Vibrio cholerae; 
#=GS C3LTY3/1-134       AC C3LTY3
#=GS C3LTY3/1-134       OS Vibrio cholerae M66-2
#=GS C3LTY3/1-134       DE Response regulator
#=GS C3LTY3/1-134       DR GENE3D; 1c930dca0238f6dbba51cf23a88cafa5/1-134; 
#=GS C3LTY3/1-134       DR ORG; Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae; Vibrio; Vibrio cholerae; 
#=GS A0A0X1KVF0/1-134   AC A0A0X1KVF0
#=GS A0A0X1KVF0/1-134   OS Vibrio cholerae MO10
#=GS A0A0X1KVF0/1-134   DE Response regulator
#=GS A0A0X1KVF0/1-134   DR GENE3D; 1c930dca0238f6dbba51cf23a88cafa5/1-134; 
#=GS A0A0X1KVF0/1-134   DR ORG; Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae; Vibrio; Vibrio cholerae; 
#=GS A0A0C2BUA4/10-145  AC A0A0C2BUA4
#=GS A0A0C2BUA4/10-145  OS Herbaspirillum sp. TSA66
#=GS A0A0C2BUA4/10-145  DE Chemotaxis protein CheY
#=GS A0A0C2BUA4/10-145  DR GENE3D; 46aa1b25ac9ac60574b8c70d75d54bd3/10-145; 
#=GS A0A0C2BUA4/10-145  DR ORG; Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales; Oxalobacteraceae; Herbaspirillum; Herbaspirillum sp. TSA66; 
#=GS A0A059KMJ6/22-156  AC A0A059KMJ6
#=GS A0A059KMJ6/22-156  OS Sphaerotilus natans subsp. natans DSM 6575
#=GS A0A059KMJ6/22-156  DE Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domain protein
#=GS A0A059KMJ6/22-156  DR GENE3D; 4df48123fc5e513671b7155ee1e14ae3/22-156; 
#=GS A0A059KMJ6/22-156  DR ORG; Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales; Sphaerotilus; Sphaerotilus natans; Sphaerotilus natans subsp. natans; 
#=GS A0A1N6TB25/22-156  AC A0A1N6TB25
#=GS A0A1N6TB25/22-156  OS Sphaerotilus natans
#=GS A0A1N6TB25/22-156  DE Two-component system, NtrC family, response regulator HupR/HoxA
#=GS A0A1N6TB25/22-156  DR GENE3D; 4df48123fc5e513671b7155ee1e14ae3/22-156; 
#=GS A0A1N6TB25/22-156  DR ORG; Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales; Sphaerotilus; Sphaerotilus natans; 
#=GS A0A1F4H5T8/1-139   AC A0A1F4H5T8
#=GS A0A1F4H5T8/1-139   OS Burkholderiales bacterium GWF1_66_17
#=GS A0A1F4H5T8/1-139   DE Sigma-54-dependent Fis family transcriptional regulator
#=GS A0A1F4H5T8/1-139   DR GENE3D; 51f4fa4ab5afbdb3303a6cf9afc34903/1-139; 
#=GS A0A1F4H5T8/1-139   DR ORG; Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales; Burkholderiales bacterium GWF1_66_17; 
#=GS A0A167ILI8/10-147  AC A0A167ILI8
#=GS A0A167ILI8/10-147  OS Hydrogenophaga sp. LPB0072
#=GS A0A167ILI8/10-147  DE Sigma-54-dependent Fis family transcriptional regulator
#=GS A0A167ILI8/10-147  DR GENE3D; 53e712a2288754b0aa51fef1850b0d06/10-147; 
#=GS A0A167ILI8/10-147  DR ORG; Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales; Comamonadaceae; Hydrogenophaga; Hydrogenophaga sp. LPB0072; 
#=GS D0IFX3/2-136       AC D0IFX3
#=GS D0IFX3/2-136       OS Vibrio sp. RC586
#=GS D0IFX3/2-136       DE Diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(S)
#=GS D0IFX3/2-136       DR GENE3D; 5fa05fc186844a4a1f09d8c85619853f/2-136; 
#=GS D0IFX3/2-136       DR ORG; Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae; Vibrio; Vibrio sp. RC586; 
#=GS P29267/6-140       AC P29267
#=GS P29267/6-140       OS Ralstonia eutropha H16
#=GS P29267/6-140       DE Hydrogenase transcriptional regulatory protein HoxA
#=GS P29267/6-140       DR GENE3D; ce87cd0da56f8c35d3ece9b3a7545446/6-140; 
#=GS P29267/6-140       DR ORG; Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales; Burkholderiaceae; Cupriavidus; Cupriavidus necator; 
#=GS D2YPZ0/3-141       AC D2YPZ0
#=GS D2YPZ0/3-141       OS Vibrio mimicus VM573
#=GS D2YPZ0/3-141       DE Response regulator
#=GS D2YPZ0/3-141       DR GENE3D; e1457edf55296dcafa6b19c1f63c77b5/3-141; 
#=GS D2YPZ0/3-141       DR ORG; Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae; Vibrio; Vibrio mimicus; 
#=GS A0A0Q0UFI4/1-138   AC A0A0Q0UFI4
#=GS A0A0Q0UFI4/1-138   OS Vibrio metoecus
#=GS A0A0Q0UFI4/1-138   DE Diguanylate phosphodiesterase
#=GS A0A0Q0UFI4/1-138   DR GENE3D; f5a6b42b9b743fc7bf06e232521a7fda/1-138; 
#=GS A0A0Q0UFI4/1-138   DR ORG; Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae; Vibrio; Vibrio metoecus; 
#=GS D0HFR0/3-135       AC D0HFR0
#=GS D0HFR0/3-135       OS Vibrio mimicus VM223
#=GS D0HFR0/3-135       DE Diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(S)
#=GS D0HFR0/3-135       DR GENE3D; f81db30b4099262aa465574cb56ba34c/3-135; 
#=GS D0HFR0/3-135       DR ORG; Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae; Vibrio; Vibrio mimicus; 
#=GS A0A1L5MJH6/5-138   AC A0A1L5MJH6
#=GS A0A1L5MJH6/5-138   OS Bradyrhizobium diazoefficiens
#=GS A0A1L5MJH6/5-138   DE Two-component system response regulator
#=GS A0A1L5MJH6/5-138   DR GENE3D; f8ffddd9c8d0a5044165741a0ea36ad6/5-138; 
#=GS A0A1L5MJH6/5-138   DR ORG; Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales; Bradyrhizobiaceae; Bradyrhizobium; Bradyrhizobium diazoefficiens; 
#=GS A0A0M9BA44/5-138   AC A0A0M9BA44
#=GS A0A0M9BA44/5-138   OS Bradyrhizobium japonicum
#=GS A0A0M9BA44/5-138   DE Chemotaxis protein CheY
#=GS A0A0M9BA44/5-138   DR GENE3D; f8ffddd9c8d0a5044165741a0ea36ad6/5-138; 
#=GS A0A0M9BA44/5-138   DR ORG; Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales; Bradyrhizobiaceae; Bradyrhizobium; Bradyrhizobium japonicum; 
#=GF TC 209.3 6.7E-66
#=GF SQ 19
Q9KT19/1-134               MQSNREILLVDDEPAVLNALKRELRPYFPHLHTATCAQEALELLKQHPVQMVISDYRMPGMNGADLVIEINRRYPHIMSLILSGQADMNGLSRALNEGDLYKFLLKPWERNYLLQTILQCFSEKERREEFDTVS---------
P31908/5-138               ----GTILVVDDEVRSQEALRRVLREDFEVL-CVGNATDAEKLLEGEIVHAILCDQRMPHESGVSFLKRVRELWPDPVRMIISGYSESEDIIAGLNEAGIYQYITKPWQPDQLVETVKEAVQLYRLQKETETAGVDVKA----
A0A0K9UTJ2/1-134           MQSNREILLVDDEPAVLNALKRELRPYFPHLHTATCAQEALELLKQHPVQMVISDYRMPGMNGADLVIEINRRYPHIMSLILSGQADMNGLSRALNEGDLYKFLLKPWERNYLLQTILQCFSEKERREEFDTVS---------
A0A0H6KNA5/1-134           MQSNREILLVDDEPAVLNALKRELRPYFPHLHTATCAQEALELLKQHPVQMVISDYRMPGMNGADLVIEINRRYPHIMSLILSGQADMNGLSRALNEGDLYKFLLKPWERNYLLQTILQCFSEKERREEFDTVS---------
A0A0H3PX26/1-134           MQSNREILLVDDEPAVLNALKRELRPYFPHLHTATCAQEALELLKQHPVQMVISDYRMPGMNGADLVIEINRRYPHIMSLILSGQADMNGLSRALNEGDLYKFLLKPWERNYLLQTILQCFSEKERREEFDTVS---------
C3LTY3/1-134               MQSNREILLVDDEPAVLNALKRELRPYFPHLHTATCAQEALELLKQHPVQMVISDYRMPGMNGADLVIEINRRYPHIMSLILSGQADMNGLSRALNEGDLYKFLLKPWERNYLLQTILQCFSEKERREEFDTVS---------
A0A0X1KVF0/1-134           MQSNREILLVDDEPAVLNALKRELRPYFPHLHTATCAQEALELLKQHPVQMVISDYRMPGMNGADLVIEINRRYPHIMSLILSGQADMNGLSRALNEGDLYKFLLKPWERNYLLQTILQCFSEKERREEFDTVS---------
A0A0C2BUA4/10-145          ----STVLVIDDETRSQDAIRRTLDEDFNVL-TAGSADEGRAVLERQQVAVVLCDQRMPGMTGVQFLKEVRERWPDVVRIVISGYTDSEDIIEGINEAGIYQYLLKPWLPDHLLDTVRRAVDARSLQSDMHRINLELRTSA--
A0A059KMJ6/22-156          ---LPLVLLVDDEVRSQDAMRRTLDEDFRIL-CASSAEEARALLERHEAAVILCDQRMPGLTGVEFLREVRERWPETVRIVISGYTDSEDIIRGINEAGIYQYILKPWVPDHLLQTVRQAVEARTLQRGVSRLELDLRA----
A0A1N6TB25/22-156          ---LPLVLLVDDEVRSQDAMRRTLDEDFRIL-CASSAEEARALLERHEAAVILCDQRMPGLTGVEFLREVRERWPETVRIVISGYTDSEDIIRGINEAGIYQYILKPWVPDHLLQTVRQAVEARTLQRGVSRLELDLRA----
A0A1F4H5T8/1-139           ---MPTVLVVDDEVRSQDAMRRTLDEDFTVF-TASSAEEARGLLERQPVSVILCDQRMPGVTGVTFLKEVRERWPETVRIVISGYTDSEDIIAGINEAGIYQYILKPWAPDHLLDSVRNAVEAQALQRQTSRLDLELRTSNRV
A0A167ILI8/10-147          ---LPTVLVVDDEVRSLDAIRRTLDEDFTVF-TASSAEEARGLLERQAVSVILCDQRMPGQTGVNFLKQVRERWPEVVRIVISGYTDSEDIIAGINEAGVYQYILKPWSPDHLLDSVRNAVEAQTLQRQTSRLDLELRTST-V
D0IFX3/2-136               -YASREILLVDDEPAVLNALKRELRPYFPNLYTATCAQEALEVLKQHSIQMVISDYRMPGMNGADLVIEINRHYPQIMSLILSGQADMDGLSRALNEGELYKFLLKPWDRTYLLQTILQCFSEKERQQEFNSIT-GL------
P29267/6-140               ----ATVLVVDDETRSQDALRRTLDEEFRVL-TVSSADEARALLLRQPVSVILCDQRMPGLTGVEFLKEVRERWPEIVRIVISGYTDSEDIIAGVNEAGIYQYILKPWVPDHLIDTVRQAVEAQGLQGDMHRLDLELRTS---
D2YPZ0/3-141               --VNREILLVDDEPAVLNALKRELRPYFPHLYTATCGQEALEVLQQHPVQMVISDYRMPGMNGADLVIEINRRYPQIMSLILSGQADFDGLSRALNEGELYKFLLKPWDRTYLLHTILQCFSELDRQQEFNAVS-GLKTVQ-A
A0A0Q0UFI4/1-138           MQANREILLVDDEPAVLNALKRELRPYFSHLYTATCAQEALEILQQHPIQMVISDYRMPGMNGADLVIEINRRYPQIMSLILSGQADMDGLSRALNEGDLYKFLLKPWDRAYLLQTIMHCFSELDREQEFNATS-GLKT----
D0HFR0/3-135               --VNREILLVDDEPAVLNALKRELRPYFPHLYTATCGQEALEVLQQHPVQMVISDYRMPGMNGADLVIEINRRYPQIMSLILSGQADFDGLSRALNEGELYKFLLKPWDRTYLLHTILQCFSELDRQQEFNAVS-G-------
A0A1L5MJH6/5-138           ----GTILVVDDEVRSQEALRRVLREDFEVL-CVGNATDAEKLLEGEIVHAILCDQRMPHESGVSFLKRVRELWPDPVRMIISGYSESEDIIAGLNEAGIYQYITKPWQPDQLVETVKEAVQLYRLQKETETAGVDVKA----
A0A0M9BA44/5-138           ----GTILVVDDEVRSQEALRRVLREDFEVL-CVGNATDAEKLLEGEIVHAILCDQRMPHESGVSFLKRVRELWPDPVRMIISGYSESEDIIAGLNEAGIYQYITKPWQPDQLVETVKEAVQLYRLQKETETAGVDVKA----
#=GC scorecons             00124479689995555596794955494471665584783479555474576695999645964664675565945656769955756665566996569676699935559757745554433464644444123220000
#=GC scorecons_70          ______*******_____****_*___*__*__*__*_**__**____*__**_*_****__*__**_**____*__*__****__*___*___***___********____**_**_________*________________
#=GC scorecons_80          ______**_****_____*__*_*___*__*_____*_**___*____*_____*_***___*___________*_____*_**__*________**___*_*__***____*__*___________________________
#=GC scorecons_90          _______*_****_____*__*_*___*___________*___*__________*_***___*___________*_______**___________**___*____***____*______________________________
//