The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was: waiting to be named.
3.90.70.100
superfamily
Functional Families
Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
Superfamily: Tymovirus endopeptidases
Turnip yellow mosaic virus, or TYMV, is a member of the alphavirus-like supergroup of viruses and is a good model system for postitive-stranded RNA virus membrane bound replication. TYMV encodes a precursor replication polyprotein that is processed by the endoproteolytic activity of its internal cysteine proteinase domain. It also displays ubiquitin hydrolase (DUB) activity which is a key factor for the interaction of the virus with its host (enables counteracting the ubiquitin-proteasome system).
This entry represents the cysteine proteinase domain which exhibits a papain-like fold. The fold consists of two subdomains with the active site between them. One subdomain consists of a bundle of helices, with the catalytic Cys at the end of one of them, and the other subdomain is a beta-barrel with the active site His and Asn (or Asp).
GO Diversity
Unique GO annotations
0 Unique GO terms
EC Diversity
Unique EC annotations
2 Unique EC terms
Species Diversity
Unique species annotations
52 Unique species
Sequence/Structure Diversity
Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.
Superfamily Summary
A general summary of information for this superfamily.
| Structures | |
|---|---|
| Domains: | 5 |
| Domain clusters (>95% seq id): | 1 |
| Domain clusters (>35% seq id): | 1 |
| Unique PDBs: | 3 |
| Alignments | |
| Structural Clusters (5A): | 1 |
| Structural Clusters (9A): | 1 |
| FunFam Clusters: | 0 |
| Function | |
| Unique EC: | 2 |
| Unique GO: | |
| Taxonomy | |
| Unique Species: | 52 |
