The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Dihydrofolate Reductase, subunit A
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
1
658
3D
7dfrA00 - 93.8
4
139
3D
4elhH00 - 42.1
2
132
3D
3k47A00 - 96.5
3
72 - - 69.1
7
56
3D
3dgaB00 - 83.4
5
51 - - 41.6
6
48
3D
2obcB02 - 78.9
24
38
3D
4hofB00 - 8.3
9
23
3D
3ix9B00 - 85.6
22
21
3D
4g3mD02 - 0.0
8
18 - - 12.1
11
18
3D
4ha9B00 - 92.3
16
5-phosphoribosylamino
16
3D
4xt8A00 - 0.0
10
15 - - 35.5
12
13 - - 5.1
13
13 - - 76.2
14
11 - - 16.6
17
11
3D
3rg9B00 - 44.2
15
10 - - 37.5
18
7 - - 75.4
25
6
3D
2xw7B00 - 11.3
19
6 - - 0.0
37
6
3D
1d1gB00 - 0.0
20
5 - - 11.2
21
5 - - 0.0
29
4 - - 9.9
26
4 - - 0.0
27
4 - - 12.9
23
4 - - 47.8
28
4 - - 73.7
32
3 - - 7.3
31
3 - - 6.2
33
3 - - 15.6
30
3 - - 60.6
39
2 - - 7.0
35
2 - - 2.0
36
2 - - 0.0
40
2 - - 0.0
41
2 - - 1.1
43
2 - - 6.0
38
Eurofung
2 - - 0.0
42
2 - - 0.0
34
2 - - 33.9
51
1 - - 0.0
48
1 - - 0.0
55
1 - - 0.0
57
1 - - 0.0
46
1 - - 0.0
45
1 - - 0.0
52
1 - - 0.0
53
1 - - 0.0
44
1 - - 0.0
49
1 - - 0.0
50
1 - - 0.0
47
1 - - 0.0
56
1 - - 0.0
54
1 - - 0.0