The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: GspL cytoplasmic domain, C-terminal subdomain

The type II secretion system (T2SS) is present in many Gram-negative bacteria and is responsible for secreting a large number of folded proteins, including major virulence factors, across the outer membrane. GspL (known in Vibrio species as EpsL) is a T2SS protein which interacts with several other T2SS proteins. The cytoplasmic domain of GspL (cyto-GspL) is responsible for the interactions with the first domain of GspE (an ATPase) and consists of three subdomains with similarities to proteins belonging to the actin-like ATPase superfamily. This entry represents the C-terminal subdomain of cyto-GspL PMID:25092625.

GO Diversity

Unique GO annotations
4 Unique GO terms

EC Diversity

Unique EC annotations
0 Unique EC terms

Species Diversity

Unique species annotations
545 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Domains: 8
Domain clusters (>95% seq id): 3
Domain clusters (>35% seq id): 3
Unique PDBs: 5
Structural Clusters (5A): 1
Structural Clusters (9A): 1
FunFam Clusters: 2
Unique EC:
Unique GO: 4
Unique Species: 545