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CATH Superfamily 3.30.1490.200

Penicillin-binding protein Tp47, domain A

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Penicillin-binding protein Tp47, domain A
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: Penicillin-binding protein Tp47, domain A

Structural domains comprising this superfamily share the structure of domain A of the unusual penicillin-binding protein (PBP), Tp47. Tp47 is unusual in that it displays beta-lactamase activity, so it does not fit the classical PBP archetype, and thus it appears to represent a new class of PBP. Domains A is mainly composed of beta-strands and is sequentially non-contiguous. The first three domains in Tp47 interact closely with each other through intimate domain-domain interfaces. Domain A contacts domain B through its N-terminal segment and it also interacts tightly with domain C PMID:12196546.

GO Diversity

Unique GO annotations
1 Unique GO terms

EC Diversity

Unique EC annotations
0 Unique EC terms

Species Diversity

Unique species annotations
10 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Structures
Domains: 2
Domain clusters (>95% seq id): 1
Domain clusters (>35% seq id): 1
Unique PDBs: 1
Alignments
Structural Clusters (5A): 1
Structural Clusters (9A): 1
FunFam Clusters: 1
Function
Unique EC:
Unique GO: 1
Taxonomy
Unique Species: 10