The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

Pantoate-beta-alanine ligase, C-terminal domain

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: Pantoate-beta-alanine ligase, C-terminal domain

According to the literature, members of the structural domains which comprise this superfamily correspond to the structure of the C-terminal domain of a pantoate-beta-alanine ligase, also known as pantoate-beta-alanine synthase, which catalyses the formation of pantothenate from pantoate and alanine in the pantothenate biosynthesis pathway. Its C-terminal domain partially covers the active site cavity in the N-terminal domain and it has been proposed that a hinged movement of this domains is reponsible for the opening and closing of the active site PMID:12717031.

GO Diversity

Unique GO annotations
15 Unique GO terms

EC Diversity

Unique EC annotations
2 Unique EC terms

Species Diversity

Unique species annotations
10726 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Domains: 137
Domain clusters (>95% seq id): 12
Domain clusters (>35% seq id): 4
Unique PDBs: 68
Structural Clusters (5A): 1
Structural Clusters (9A): 1
FunFam Clusters: 18
Unique EC: 2
Unique GO: 15
Unique Species: 10726