The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

Ribosomal protein L24e

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: Ribosomal protein L24

Structural domains comprising this superfamily share the structure of the ribosomal protein L24, found in eukaryotes (L24) and archaea (L24e, different from L24) and located on the surface of the large subunit, adjacent to proteins L14 and L3, and near the translation factor binding site. L24e/L24 appears to be involved in the kinetics of peptide synthesis, and it has been suggested to mediate interactions between the large and small subunits, directly or through other factors. The protein is composed of a single structural domain which forms an alpha/beta zinc-binding fold.

In mouse, a deletion mutation in L24 has been identified as the cause for the belly spot and tail (Bst) mutation that results in disrupted pigmentation, somitogenesis and retinal cell fate determination PMID:15289434. L24 may be an important protein in eukaryotic reproduction: in shrimp, L24 expression is elevated in the ovary, suggesting a role in oogenesis, and in Arabidopsis, L24 has been proposed to have a specific function in gynoecium development PMID:17462931,PMID:15270688.


GO Diversity

Unique GO annotations
42 Unique GO terms

EC Diversity

Unique EC annotations
0 Unique EC terms

Species Diversity

Unique species annotations
2321 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Domains: 120
Domain clusters (>95% seq id): 7
Domain clusters (>35% seq id): 4
Unique PDBs: 120
Structural Clusters (5A): 1
Structural Clusters (9A): 1
FunFam Clusters: 21
Unique EC:
Unique GO: 42
Unique Species: 2321