The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: Uncharacterised protein UvsW.1

The uvsWXY system is implicated in the replication and repair of the bacteriophage T4 genome. UvsW is a member of the monomeric SF2 helicase superfamily that translocates nucleic acid substrates via the action of two RecA-like motor domains. A sequencing error at the 3-end of the uvsW gene has revealed a second, short open reading frame that encodes a protein of unknown function called UvsW.1.

This entry represents UvsW.1, which exhibits a dynamic four-helix bundle structure. Helices 2, 3 and 4 form a rigid 3-helix bundle while helix 1 is separate from the core. This protein is a highly conserved protein in T4-related viruses. The only major differences are insertions and deletions in either the linker between helices 1 and 2, or the C-terminus. PMID:17878153

GO Diversity

Unique GO annotations
0 Unique GO terms

EC Diversity

Unique EC annotations
1 Unique EC terms

Species Diversity

Unique species annotations
187 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Domains: 1
Domain clusters (>95% seq id): 1
Domain clusters (>35% seq id): 1
Unique PDBs: 1
Structural Clusters (5A): 1
Structural Clusters (9A): 1
FunFam Clusters: 0
Unique EC: 1
Unique GO:
Unique Species: 187