The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

Serine carboxypeptidase S28, SKS domain

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: Serine carboxypeptidase S28, SKS domain

Serine carboxypeptidase S28 family comprises carboxypeptidase PRCP and the aminopeptidase DPP7. The cap domain (SKS) is formed by 11 alpha-helices and two strands interconnected by loops. It contains four disulphide bonds which are assumed to be involved in stabilising the structure. According to literature and pfam, the SKS domain is a rare fold possibly present only in the S28 serine peptidase family. DOI:10.1186/1472-6807-10-16,DOI:10.1371/journal.pone.0043019

GO Diversity

Unique GO annotations
34 Unique GO terms

EC Diversity

Unique EC annotations
2 Unique EC terms

Species Diversity

Unique species annotations
786 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Domains: 11
Domain clusters (>95% seq id): 2
Domain clusters (>35% seq id): 2
Unique PDBs: 4
Structural Clusters (5A): 1
Structural Clusters (9A): 1
FunFam Clusters: 61
Unique EC: 2
Unique GO: 34
Unique Species: 786