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CATH Superfamily 1.10.520.40

CRISPR-associated protein Cse2

The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
CRISPR-associated protein Cse2
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: CRISPR-associated protein Cse2

Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) are a family of DNA direct repeats separated by regularly sized non-repetitive spacer sequences that are found in most bacterial and archaeal genomes PMID:17442114. The CRISPR-associated (Cas) proteins are encoded in the vicinity of the CRISPRs. The CRISPR systems (CRISPRs and Cas proteins) are classified into several subtypes, and each subtype contains several different subtype specific cas genes.It was shown that one of the Cas proteins, Cse2, comprises a novel family of endoribonucleases, and cleaves single-stranded RNAs preferentially within U-rich regions PMID:18798563 .

This entry represents Cse2 which is made up of nine alpha-helices.

PMID:17442114 PMID:18798563

GO Diversity

Unique GO annotations
5 Unique GO terms

EC Diversity

Unique EC annotations
0 Unique EC terms

Species Diversity

Unique species annotations
1480 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Structures
Domains: 25
Domain clusters (>95% seq id): 5
Domain clusters (>35% seq id): 4
Unique PDBs: 11
Alignments
Structural Clusters (5A): 1
Structural Clusters (9A): 1
FunFam Clusters: 2
Function
Unique EC:
Unique GO: 5
Taxonomy
Unique Species: 1480
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