CATH Superfamily 1.10.246.130

Gamma-glutamyltranspeptidase, large (L) subunit, C-terminal domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was: waiting to be named.

Home /
Superfamily 1.10.246.130

1.10.246.130

superfamily

Superfamily Links
Summary
Superfamily Superposition
Classification / Domains
Functional Families
Structural Neighbourhood

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: Gamma-glutamyltranspeptidase, large (L) subunit, C-terminal domain

Gamma-glutamyltranspeptidase (GGT) is a heterodimic enzyme that is generated from the precursor protein through posttranslational processing and catalyzes the hydrolysis of gamma-glutamyl bonds in gamma-glutamyl compounds. GGT has a stacked alpha-beta-beta-alpha fold comprising the large and small subunits, similar to the folds seen in members of the N-terminal nucleophile hydrolase superfamily. This entry represents the C-terminal domain of the large subunit PMID:16618936.

GO Diversity

Unique GO annotations

58 Unique GO terms

EC Diversity

Unique EC annotations

5 Unique EC terms

Species Diversity

Unique species annotations

8479 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.

Structures
Domains:	51
Domain clusters (>95% seq id):	6
Domain clusters (>35% seq id):	4
Unique PDBs:	33
Alignments
Structural Clusters (5A):	1
Structural Clusters (9A):	1
FunFam Clusters:	29
Function
Unique EC:	5
Unique GO:	58
Taxonomy
Unique Species:	8479

Network disruptions