The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

Erythrocyte binding antigen 175 region VI

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: Erythrocyte binding antigen 175 region VI

Structural domains which comprise this superfamily correspond to the structure of the highly conserved region VI of the erythrocyte-binding antigen 175 (EBA-175) of the malaria parasite Plasmodium falciparum. EBA-175 belongs to erythrocyte-binding protein family involved in the formation of a tight junction, a necessary step in invasion of erythrocytes, a step required for replication and proliferation of the parasite in the bloodstream of its vertebrate host. Region VI is a cysteine-rich domain essential for EBA-175 trafficking. PMID:18036613

GO Diversity

Unique GO annotations
13 Unique GO terms

EC Diversity

Unique EC annotations
0 Unique EC terms

Species Diversity

Unique species annotations
51 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Domains: 2
Domain clusters (>95% seq id): 1
Domain clusters (>35% seq id): 1
Unique PDBs: 1
Structural Clusters (5A): 1
Structural Clusters (9A): 1
FunFam Clusters: 1
Unique EC:
Unique GO: 13
Unique Species: 51