The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

Glutamate cysteine ligase subdomain

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: Glutamate cysteine ligase subdomain

The structure of the representative domain for this superfamily maps to a Pfam domain which belongs to a family named glutamate cysteine ligase. However, it maps only to a segment of this Pfam domain and therefore, in the absence of any information on this representative domain, the term subdomain has been introduced to design this superfamily.

This nomenclature is consistent with UniProt-SwissProt, EC and GO entries, all of which highlight the role of this superfamily in glutamate-cysteine ligation.

GO Diversity

Unique GO annotations
6 Unique GO terms

EC Diversity

Unique EC annotations
1 Unique EC terms

Species Diversity

Unique species annotations
54 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Domains: 4
Domain clusters (>95% seq id): 1
Domain clusters (>35% seq id): 1
Unique PDBs: 4
Structural Clusters (5A): 1
Structural Clusters (9A): 1
FunFam Clusters: 1
Unique EC: 1
Unique GO: 6
Unique Species: 54