CATH Superfamily 1.10.150.20

Browse Functional Families

ID	Function Family (FunFam) Name	Total Sequences	Structure?	Structural Representative	PDB Sites?	Alignment Diversity (0-100)
1	DNA-directed RNA polymerase subunit alpha	4620	3D	6gh5A03	-	92.6
2	DNA polymerase I	910	3D	2kzzA04	-	94.4
3	DNA polymerase I	710	3D	3zdeA02	-	99.3
4	U5 small nuclear ribonucleoprotein helicase	614	3D	4kitB05	-	99.5
10	DNA polymerase lambda	612	3D	5iioM02	-	99.0
5	UvrABC system protein C	582	3D	1kftA00	-	96.0
26	DNA polymerase beta	553	3D	9icyA02	-	89.0
6	DNA ligase	518	3D	5tt5A05	-	98.8
7	DNA ligase	504	3D	5tt5A04	-	100.0
14	Polymerase DNA directed	465	3D	6mxoA03	-	96.6
8	DNA repair protein RAD51 homolog	464	3D	3ldaA01	-	95.9
9	Flap endonuclease 1	434		-	-	96.8
11	exonuclease 1	422	3D	5v0eZ02	-	98.6
12	Holliday junction ATP-dependent DNA helicase RuvA	395	3D	1hjpA02	-	58.8
13	U5 small nuclear ribonucleoprotein kDa helicase	393	3D	4kitB11	-	99.1
15	Transcription termination/antitermination protein NusA	331	3D	2jzbB01	-	79.8
16	DNA integrity scanning protein DisA	327		-	-	69.7
19	DNA polymerase IV	309	3D	6ig1F03	-	96.5
17	DNA excision repair protein ERCC-1	271	3D	2mutA00	-	96.4
18	Transcription termination/antitermination protein NusA	260	3D	1wclA00	-	83.1
20	DNA-directed RNA polymerase subunit alpha	242		-	-	40.5
21	DNA-directed RNA polymerase subunit alpha	237		-	-	72.3
22	translocation protein SEC63 homolog	230		-	-	92.4
23	DNA integrity scanning protein DisA	223		-	-	76.0
24	DNA polymerase gamma, catalytic subunit	217		-	-	75.1
25	DNA repair protein REV1	168	3D	3gqcD03	-	85.0
27	DNA-directed RNA polymerase	153		-	-	78.3
28	activating signal cointegrator 1 complex subunit 3	152		-	-	88.8
29	DNA repair protein RAD51 homolog	143	3D	1b22A00	-	60.6
30	Flap endonuclease GEN-like 1	140		-	-	94.9
31	DNA-directed RNA polymerase	138		-	-	85.6
32	meiotic recombination protein DMC1/LIM15 homolog	128		-	-	81.1
33	TfoX family protein	127		-	-	0.0
34	DNA polymerase I	126		-	-	69.8
35	DNA polymerase gamma, mitochondrial	122		-	-	70.9
36	Polymerase DNA directed	117		-	-	71.8
37	DNA repair protein complementing XP-G cells homolog	101		-	-	84.2
38	DNA repair endonuclease UVH1	82		-	-	89.0
40	DNA repair endonuclease XPF isoform X2	82	3D	2mutB00	-	94.4
52	DNA polymerase iota	81	3D	5ulxA03	-	35.4
39	Polymerase DNA directed	77		-	-	92.1
41	DNA-directed RNA polymerase	73		-	-	89.1
42	5'-3' exonuclease family protein	68		-	-	67.5
44	DnaJ protein ERDJ2A	66		-	-	79.1
43	Meiotic recombination protein DMC1 homolog	66		-	-	53.2
45	DNA polymerase V subunit	59		-	-	48.9
53	T5 flap endonuclease	51	3D	5hp4A02	-	17.1
46	Fanconi anemia core complex-associated protein 24	51	3D	4m6wB02	-	71.5
47	DNA-directed RNA polymerase subunit alpha	47		-	-	12.3
48	Fanconi anemia, complementation group M	46	3D	4bxoA02	-	33.9
65	DNA-directed RNA polymerase	42	3D	3e2eA05	-	18.5
49	Plastid replication-repair enzyme	42		-	-	21.2
51	Endonuclease, putative	41		-	-	25.4
50	DNA repair protein UVH3	41		-	-	81.7
59	DNA polymerase	35	3D	4p4pA01	-	54.9
54	DNA repair protein RAD51 homolog	35		-	-	11.3
56	Meiotic recombination protein DMC1	33		-	-	82.0
55	Mating-type switch/DNA repair protein Swi10/Rad10	33		-	-	70.5
57	RAD2p Single-stranded DNA endonuclease	33		-	-	83.3
58	Helicase, POLQ like	33		-	-	81.6
60	Mitochondrial DNA polymerase I protein C	32		-	-	80.3
62	DNA polymerase IV	26		-	-	47.5
123	DNA polymerase eta	26	3D	5vtpA03	-	42.9
87	Flap endonuclease 1	26	3D	1a77A02	-	89.4
61	DNA polymerase IV	26		-	-	55.2
66	Transcription termination/antitermination protein NusA	25		-	-	3.8
93	Holliday junction ATP-dependent DNA helicase RuvA	25	3D	2zteA02	-	21.1
63	DNA repair protein RAD1	25		-	-	79.6
64	Bifunctional 3'-5' exonuclease/DNA polymerase	25		-	-	31.1
67	DNA polymerase A	24		-	-	2.2
68	DNA polymerase IV	24		-	-	62.2
69	Exonuclease 1	24		-	-	8.3
70	DNA polymerase I, putative	23		-	-	92.9
71	Flap endonuclease 1	22		-	-	74.8
72	Pre-mRNA-splicing helicase BRR2, putative	20		-	-	12.0
73	Translocation protein SEC63	19		-	-	50.7
74	DNA-directed RNA polymerase	19		-	-	6.7
158	DNA integrity scanning protein DisA	19	3D	4yxmB03	-	8.2
76	DNA repair endonuclease, putative	18		-	-	8.9
75	Meiotic recombination protein DMC1	18		-	-	76.3
77	DExH-box ATP-dependent RNA helicase DExH17	18		-	-	51.1
78	DNA-directed RNA polymerase subunit alpha	18		-	-	10.2
80	Meiotic recombination protein DMC1	17		-	-	43.4
82	DNA-directed RNA polymerase, mitochondrial	17		-	-	79.7
81	Protein translocation complex component Npl1	17		-	-	61.3
83	Putative DNA polymerase 1	17		-	-	2.5
79	Putative DNA repair endonuclease	17		-	-	13.7
84	ERCC1 nucleotide excision repair protein, putative	16		-	-	3.0
85	DNA polymerase I	16		-	-	6.5
86	Translocation protein SEC63	16		-	-	24.8
88	DNA repair protein RadC	15		-	-	12.2
89	DNA repair protein	15		-	-	0.0
115	DNA repair protein REV1	15	3D	5wmbA04	-	1.4
92	DNA excision repair protein Rad2	14		-	-	51.9
91	Unplaced genomic scaffold supercont1.20, whole genome shotgun sequence	14		-	-	73.9
90	U5 small nuclear ribonucleoprotein helicase	14		-	-	17.2
96	Putative DNA polymerase kappa	13		-	-	83.4
95	Exonuclease I, putative	13		-	-	10.6
94	DNA polymerase IV	13		-	-	75.6
102	UvrABC system protein C	12		-	-	6.3
97	Meiotic recombinase Dmc1	12		-	-	53.8
98	RNA polymerase alpha subunit domain protein	12		-	-	19.3
101	Transcription termination/antitermination protein NusA	12		-	-	6.3
103	DNA-directed RNA polymerase subunit alpha	12		-	-	81.7
99	DNA ligase B	12		-	-	19.1
100	DNA ligase	12		-	-	7.6
104	Unplaced genomic scaffold supercont1.24, whole genome shotgun sequence	11		-	-	6.8
105	DNA ligase	11		-	-	20.0
107	DNA repair endonuclease XPF	11		-	-	49.6
106	5'-3' exonuclease	11		-	-	0.0
111	DNA polymerase IV	10		-	-	0.0
110	Protein CBG20918	10		-	-	42.3
109	tRNA-specific adenosine deaminase	10		-	-	13.6
108	DNA ligase	10		-	-	11.6
116	DNA ligase	9		-	-	1.6
113	DNA polymerase theta, putative	9		-	-	91.6
121	DNA-directed RNA polymerase subunit alpha	9		-	-	10.5
126	DNA repair protein RAD51 homolog	9		-	-	77.7
120	DNA-directed RNA polymerase subunit alpha	9		-	-	48.9
125	DNA polymerase subunit gamma-1, mitochondrial	9		-	-	43.1
118	flap endonuclease GEN-like 2 isoform X1	9		-	-	24.6
117	Translocation protein SEC63	9		-	-	10.2
112	DNA ligase	9		-	-	0.0
122	DNA-directed RNA polymerase subunit alpha	9		-	-	11.3
124	Exonuclease, putative	9		-	-	75.7
119	GM24241	9		-	-	22.1
114	DNA-directed RNA polymerase	9		-	-	17.4
130	5'-3' exonuclease	8		-	-	1.3
131	UvrABC system protein C	8		-	-	8.4
127	Unplaced genomic scaffold supercont1.238, whole genome shotgun sequence	8		-	-	12.4
128	DNA-directed RNA polymerase	8		-	-	22.8
129	DNA polymerase IV	8		-	-	0.0
132	Exonuclease-1, H3TH domain protein	8		-	-	81.1
161	ATP-dependent RNA helicase, putative	7	3D	1x2iB00	-	20.1
136	DNA ligase B	7		-	-	0.0
133	DNA repair protein RAD51 homolog	7		-	-	10.5
142	Exonuclease I, putative	7		-	-	8.6
141	Holliday junction ATP-dependent DNA helicase RuvA	7		-	-	7.1
138	DNA-dependent RNA polymerase	7		-	-	11.1
135	Mitochondrial DNA polymerase beta-PAK, putative	7		-	-	9.0
137	DNApol-iota, isoform A	7		-	-	14.0
157	DNA-directed DNA polymerase, family X	7	3D	2w9mB02	-	80.2
140	DNA-directed RNA polymerase subunit alpha	7		-	-	11.3
134	ImpB/MucB/SamB family protein	7		-	-	76.4
139	DNA ligase	7		-	-	3.3
153	UvrABC system protein C	6		-	-	18.1
151	Transcription termination/antitermination protein NusA	6		-	-	4.2
148	Uncharacterized protein	6		-	-	9.8
150	Predicted protein	6		-	-	24.9
145	DNA repair endonuclease xp-f, putative	6		-	-	1.7
147	Transcription termination/antitermination protein NusA	6		-	-	0.0
149	DNA ligase	6		-	-	1.8
144	DNA repair endonuclease XPF	6		-	-	7.4
146	DNaJ domain Prokaryotic heat shock protein	6		-	-	46.5
143	DNA excision repair protein, putative	6		-	-	3.2
152	UvrABC system protein C	6		-	-	0.0
163	DNA-directed RNA polymerase	5		-	-	9.2
166	DNA-directed RNA polymerase subunit alpha	5		-	-	46.1
156	FA core complex associated protein 24	5		-	-	20.2
160	5'-3' exonuclease family protein	5		-	-	0.0
165	Holliday junction ATP-dependent DNA helicase RuvA	5		-	-	1.7
155	Chromosome 8, whole genome shotgun sequence	5		-	-	13.7
167	Transcription and mRNA export factor ENY2	5		-	-	31.1
162	Probable DNA polymerase X-putative	5		-	-	14.6
154	Putative DNA repair protein	5		-	-	40.6
159	DNA polymerase lambda subunit	5		-	-	4.2
164	DNA ligase	5		-	-	16.0
178	DNA-directed RNA polymerase subunit alpha	4		-	-	8.4
177	ATP-dependent DNA helicase	4		-	-	6.4
175	ATP-dependent DNA helicase Hel308	4		-	-	13.0
172	Meiotic recombination protein Dmc1 AFU_orthologue AFUA_7G02200	4		-	-	72.3
179	DNA-directed DNA polymerase eta	4		-	-	8.4
182	Uncharacterized protein	4		-	-	11.1
174	ATP-dependent DNA helicase Hel308	4		-	-	22.6
176	DNA ligase B	4		-	-	4.6
171	UvrABC system protein C	4		-	-	0.0
180	DNA repair enzyme	4		-	-	76.6
173	DNA transformation protein TfoX1	4		-	-	16.2
170	UvrABC system protein C	4		-	-	10.0
183	Transcription termination/antitermination protein NusA	4		-	-	8.7
168	Mating-type switching protein swi10	4		-	-	5.1
181	Exonuclease I, putative	4		-	-	4.7
169	DNA repair protein Rad1 homologue, putative	4		-	-	5.1
194	DNA polymerase IV	3		-	-	0.0
187	Protein CBR-ERCC-1	3		-	-	7.0
199	DNA-directed RNA polymerase subunit alpha, chloroplastic	3		-	-	28.9
185	DNA repair endonuclease XPF	3		-	-	63.6
188	Restriction endonuclease type II-like protein	3		-	-	0.0
192	5' flap endonuclease, putative	3		-	-	6.4
189	Dmc1b	3		-	-	0.0
197	AGAP007361-PA	3		-	-	2.1
184	DNA excision repair protein ERCC-1	3		-	-	35.2
195	DNA polymerase eta	3		-	-	6.4
200	DNA damage repair protein, putative	3		-	-	0.0
198	DNA polymerase nu	3		-	-	11.9
206	Transcription termination/antitermination protein NusA	3		-	-	1.6
201	DNA polymerase IV	3		-	-	0.0
203	Flap endonuclease 1	3		-	-	2.2
204	PIN domain-like protein	3		-	-	0.0
202	Nucleotide excision repair protein	3		-	-	74.4
186	YALI0B22242p	3		-	-	0.0
208	Meiotic recombination protein DMC1	3		-	-	74.1
190	DNA-binding protein MutS2	3		-	-	20.4
205	GH27547p	3		-	-	66.4
207	UvrABC system protein C	3		-	-	0.0
193	DNA polymerase I	3		-	-	2.4
196	DNA polymerase nu	3		-	-	7.3
191	Flap structure-specific endonuclease	3		-	-	31.7
227	DNA repair protein complementing XP-G cells-like isoform X1	2		-	-	8.0
257	Flap endonuclease 1	2		-	-	0.0
218	Uncharacterized protein	2		-	-	0.0
255	DNA polymerase IV	2		-	-	5.9
225	UPF0758 protein SPO0054	2		-	-	8.0
240	DNA polymerase	2		-	-	1.9
228	DNA polymerase	2		-	-	14.7
215	Fanconi anemia core complex-associated protein 24	2		-	-	0.0
258	Flap endonuclease 1	2		-	-	0.0
217	DNA repair and recombination protein RadA	2		-	-	3.2
241	DNA polymerase nu	2		-	-	0.0
246	Uncharacterized protein	2		-	-	7.0
238	Ubiquitin carrier protein 7	2		-	-	1.4
243	Translocation protein SEC63-like protein	2		-	-	3.6
235	Uncharacterized protein	2		-	-	36.6
237	Cytosolic Fe-S cluster assembly factor NUBP1 homolog	2		-	-	9.2
254	DNA polymerase IV	2		-	-	0.0
224	DNA polymerase I	2		-	-	0.0
229	Uncharacterized protein	2		-	-	0.0
259	Probable DNA-directed RNA polymerase	2		-	-	5.0
232	DNA polymerase	2		-	-	0.0
219	UvrABC system protein C	2		-	-	0.0
214	Uncharacterized protein	2		-	-	0.0
212	AGAP002805-PA	2		-	-	4.1
222	RNA helicase, activating signal cointegrator 1	2		-	-	2.1
252	DNA polymerase IV	2		-	-	2.0
234	DNA-dependent RNA polymerase	2		-	-	0.0
239	DNA transformation protein TfoX2	2		-	-	11.6
262	50S ribosomal protein L32e	2		-	-	0.0
236	DNA transformation protein tfoX	2		-	-	10.1
231	YALI0D12364p	2		-	-	0.0
248	DNA ligase	2		-	-	2.7
210	DNA excision repair protein ERCC-1	2		-	-	30.2
220	UvrABC system protein C	2		-	-	0.0
250	DNA polymerase IV	2		-	-	9.8
245	DNA topoisomerase I	2		-	-	0.0
233	DNA polymerase	2		-	-	0.0
209	DNA ligase	2		-	-	1.5
260	DNA repair protein, putative	2		-	-	0.0
247	DNA polymerase theta	2		-	-	0.8
211	Rad10p	2		-	-	0.0
263	UvrABC system protein C	2		-	-	0.0
216	DNA repair protein RAD51 homolog	2		-	-	0.0
230	DNA polymerase	2		-	-	9.6
253	YALI0C01573p	2		-	-	0.0
223	YALI0F20724p	2		-	-	0.0
261	Protein PARTING DANCERS	2		-	-	4.1
213	DNA repair protein	2		-	-	11.9
251	DNA polymerase IV	2		-	-	0.0
256	GEN1 Holliday junction resolvase homolog	2		-	-	14.0
221	Uncharacterized protein	2		-	-	32.6
226	Protein CBR-XPG-1	2		-	-	6.8
249	DNA-directed RNA polymerase subunit alpha	2		-	-	0.0
244	Transcription termination/antitermination protein NusA	2		-	-	0.0
242	Uncharacterized protein	2		-	-	6.0
304	NADH:ubiquinone oxidoreductase 41 kD complex I subunit	1		-	-	0.0
309	Uncharacterized protein	1		-	-	0.0
265	Predicted protein	1		-	-	0.0
270	Predicted protein	1		-	-	0.0
283	Uncharacterized protein	1		-	-	0.0
333	Uncharacterized protein	1		-	-	0.0
267	Uncharacterized protein	1		-	-	0.0
320	DNA polymerase IV	1		-	-	0.0
310	DNA topoisomerase 1	1		-	-	0.0
286	UvrABC system protein C	1		-	-	0.0
268	FA core complex-associated protein 24	1		-	-	0.0
281	Uncharacterized protein	1		-	-	0.0
331	DNA-directed RNA polymerase	1		-	-	0.0
326	Uncharacterized protein	1		-	-	0.0
321	DNA polymerase IV	1		-	-	0.0
276	ERCC4 domain containing protein	1		-	-	0.0
271	Uncharacterized protein	1		-	-	0.0
313	Uncharacterized protein	1		-	-	0.0
302	Uncharacterized protein	1		-	-	0.0
323	Uncharacterized protein	1		-	-	0.0
330	Uncharacterized protein	1		-	-	0.0
280	DNA repair protein RAD51 homolog	1		-	-	0.0
273	Meiotic 9	1		-	-	0.0
316	Predicted protein	1		-	-	0.0
311	Uncharacterized protein	1		-	-	0.0
307	DNAJ domain containing protein	1		-	-	0.0
269	Uncharacterized protein	1		-	-	0.0
305	1,4-alpha-glucan branching enzyme TK1436	1		-	-	0.0
293	DNA-directed RNA polymerase	1		-	-	0.0
264	ERCC DNA excision repair protein	1		-	-	0.0
308	Uncharacterized protein	1		-	-	0.0
296	Uncharacterized protein	1		-	-	0.0
291	DNA-directed RNA polymerase	1		-	-	0.0
290	DNA nucleotidylexotransferase	1		-	-	0.0
317	Predicted protein	1		-	-	0.0
278	FA core complex-associated protein 24	1		-	-	0.0
328	Uncharacterized protein	1		-	-	0.0
315	Uncharacterized protein	1		-	-	0.0
292	DNA-directed RNA polymerase	1		-	-	0.0
318	Predicted protein	1		-	-	0.0
325	Predicted protein	1		-	-	0.0
277	FA core complex associated protein 24	1		-	-	0.0
275	DNA repair protein rad16	1		-	-	0.0
327	Xp-G/rad2 DNA repair endonuclease, putative	1		-	-	0.0
294	DNA-directed RNA polymerase	1		-	-	0.0
299	Uncharacterized protein	1		-	-	0.0
287	Uncharacterized protein	1		-	-	0.0
285	UvrABC system protein C	1		-	-	0.0
288	Uncharacterized protein	1		-	-	0.0
266	Predicted protein	1		-	-	0.0
314	Uncharacterized protein	1		-	-	0.0
319	DNA-directed RNA polymerase subunit alpha	1		-	-	0.0
300	DNA-directed RNA polymerase, mitochondrial	1		-	-	0.0
279	Uncharacterized protein	1		-	-	0.0
274	Predicted protein	1		-	-	0.0
332	Uncharacterized protein	1		-	-	0.0
282	Uncharacterized protein	1		-	-	0.0
329	RAD51 recombinase	1		-	-	0.0
324	Uncharacterized protein	1		-	-	0.0
297	PolI-like DNA polymerase	1		-	-	0.0
289	DNA-directed DNA/RNA polymerase mu	1		-	-	0.0
284	Meiotic recombination protein DMC1-like protein	1		-	-	0.0
272	Uncharacterized protein	1		-	-	0.0
334	UvrABC system protein C	1		-	-	0.0
295	DNA polymerase I family protein	1		-	-	0.0
303	Uncharacterized protein	1		-	-	0.0
322	Uncharacterized protein	1		-	-	0.0
312	DNA polymerase iota	1		-	-	0.0
298	Uncharacterized protein	1		-	-	0.0
301	DNA repair protein rev1	1		-	-	0.0
306	DNA polymerase eta	1		-	-	0.0

Network disruptions

CATH Superfamily 1.10.150.20

5' to 3' exonuclease, C-terminal subdomain

Functional Families

Browse Functional Families