CATH Classification

Domain Context

CATH Clusters

Superfamily DNA Methylase, subunit A, domain 2
Functional Family

Enzyme Information

2.1.1.37
DNA (cytosine-5-)-methyltransferase.
based on mapping to UniProt P05102
S-adenosyl-L-methionine + DNA = S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine.
-!- See the REBASE database for a complete list of these enzymes: http://rebase.neb.com/rebase/ -!- Formerly EC 2.1.1.73.

UniProtKB Entries (1)

P05102
MTH1_HAEPH
Haemophilus parahaemolyticus
Modification methylase HhaI

PDB Structure

PDB 8MHT
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structures of HhaI methyltransferase complexed with substrates containing mismatches at the target base.
O'Gara, M., Horton, J.R., Roberts, R.J., Cheng, X.
Nat.Struct.Biol.