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1 keywords

CATH Domain 6qaeA00

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.40 3-Layer(aba) Sandwich
Topology 3.40.50 Rossmann fold
Homologous Superfamily 3.40.50.1820 alpha/beta hydrolase

Domain Context

CATH Clusters

Superfamily alpha/beta hydrolase
Functional Family Acetylcholinesterase

Enzyme Information

3.1.1.8
Cholinesterase.
based on mapping to UniProt P06276
An acylcholine + H(2)O = choline + a carboxylate.
-!- Acts on a variety of choline esters and a few other compounds.

UniProtKB Entries (1)

P06276
CHLE_HUMAN
Homo sapiens
Cholinesterase

PDB Structure

PDB 6QAE
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Tryptophan-derived butyrylcholinesterase inhibitors as promising leads against Alzheimer's disease.
Meden, A., Knez, D., Jukic, M., Brazzolotto, X., Grsic, M., Pislar, A., Zahirovic, A., Kos, J., Nachon, F., Svete, J., Gobec, S., Groselj, U.
Chem.Commun.(Camb.)
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