CATH Classification

Domain Context

CATH Clusters

Superfamily 3.10.450.50
Functional Family

Enzyme Information

2.7.11.17
Calcium/calmodulin-dependent protein kinase.
based on mapping to UniProt Q9UQM7
ATP + a protein = ADP + a phosphoprotein.
-!- Requires calmodulin. -!- A wide range of proteins can act as acceptor, including vimentin, synapsin, glycogen synthase, myosin light-chains and the microtubule- associated tau protein. -!- Not identical with EC 2.7.11.18 or EC 2.7.11.26. -!- Formerly EC 2.7.1.120 and EC 2.7.1.123.

UniProtKB Entries (1)

Q9UQM7
KCC2A_HUMAN
Homo sapiens
Calcium/calmodulin-dependent protein kinase type II subunit alpha

PDB Structure

PDB 6OF8
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Variation in assembly stoichiometry in non-metazoan homologs of the hub domain of Ca2+/calmodulin-dependent protein kinase II.
McSpadden, E.D., Xia, Z., Chi, C.C., Susa, A.C., Shah, N.H., Gee, C.L., Williams, E.R., Kuriyan, J.
Protein Sci.