CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.630 | Aminopeptidase |
|
3.40.630.10 | Zn peptidases |
Domain Context
CATH Clusters
| Superfamily | Zn peptidases |
| Functional Family | Carboxypeptidase A1 |
Enzyme Information
| 3.4.17.1 |
Carboxypeptidase A.
based on mapping to UniProt P15085
Release of a C-terminal amino acid, but little or no action with -Asp, -Glu, -Arg, -Lys or -Pro.
-!- Isolated from cattle, pig and dogfish pancreas, and other sources including mast cells and skeletal muscle. -!- Belongs to peptidase family M14. -!- Formerly EC 3.4.2.1 and EC 3.4.12.2.
|
UniProtKB Entries (1)
| P15085 |
CBPA1_HUMAN
Homo sapiens
Carboxypeptidase A1
|
PDB Structure
| PDB | 6I6Z |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Synthesis and Structural/Functional Characterization of Selective M14 Metallocarboxypeptidase Inhibitors Based on Phosphinic Pseudopeptide Scaffold: Implications on the Design of Specific Optical Probes.
J. Med. Chem.
|
