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1 keywords

CATH Domain 6httB00

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.40 3-Layer(aba) Sandwich
Topology 3.40.800 Arginase; Chain A
Homologous Superfamily 3.40.800.20 Histone deacetylase domain

Domain Context

CATH Clusters

Superfamily Histone deacetylase domain
Functional Family

Enzyme Information

UniProtKB Entries (1)

A5H660
A5H660_SCHMA
Schistosoma mansoni
Histone deacetylase 8

PDB Structure

PDB 6HTT
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Characterization of Histone Deacetylase 8 (HDAC8) Selective Inhibition Reveals Specific Active Site Structural and Functional Determinants.
Marek, M., Shaik, T.B., Heimburg, T., Chakrabarti, A., Lancelot, J., Ramos-Morales, E., Da Veiga, C., Kalinin, D., Melesina, J., Robaa, D., Schmidtkunz, K., Suzuki, T., Holl, R., Ennifar, E., Pierce, R.J., Jung, M., Sippl, W., Romier, C.
J. Med. Chem.
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