CATH Classification

Domain Context

CATH Clusters

Superfamily von Hippel-Lindau disease tumour suppressor, alpha domain
Functional Family von Hippel-Lindau disease tumor suppressor

Enzyme Information

UniProtKB Entries (1)

P40337
VHL_HUMAN
Homo sapiens
Von Hippel-Lindau disease tumor suppressor

PDB Structure

PDB 6GFX
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
3-Fluoro-4-hydroxyprolines: Synthesis, Conformational Analysis, and Stereoselective Recognition by the VHL E3 Ubiquitin Ligase for Targeted Protein Degradation.
Testa, A., Lucas, X., Castro, G.V., Chan, K.H., Wright, J.E., Runcie, A.C., Gadd, M.S., Harrison, W.T.A., Ko, E.J., Fletcher, D., Ciulli, A.
J. Am. Chem. Soc.