CATH Classification

Domain Context

CATH Clusters

Superfamily NAD(P)-binding Rossmann-like Domain
Functional Family Pteridine reductase

Enzyme Information

UniProtKB Entries (1)

O76290
O76290_TRYBB
Trypanosoma brucei brucei
Pteridine reductase

PDB Structure

PDB 6GDO
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Enhancement of Benzothiazoles as Pteridine Reductase-1 Inhibitors for the Treatment of Trypanosomatidic Infections.
Linciano, P., Pozzi, C., Iacono, L.D., di Pisa, F., Landi, G., Bonucci, A., Gul, S., Kuzikov, M., Ellinger, B., Witt, G., Santarem, N., Baptista, C., Franco, C., Moraes, C.B., Muller, W., Wittig, U., Luciani, R., Sesenna, A., Quotadamo, A., Ferrari, S., Pohner, I., Cordeiro-da-Silva, A., Mangani, S., Costantino, L., Costi, M.P.
J.Med.Chem.
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