CATH Classification

Domain Context

CATH Clusters

Superfamily Helix-loop-helix DNA-binding domain
Functional Family microphthalmia-associated transcription factor isoform X1

Enzyme Information

UniProtKB Entries (1)

Q08874
MITF_MOUSE
Mus musculus
Microphthalmia-associated transcription factor

PDB Structure

PDB 6G1L
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
MITF has a central role in regulating starvation-induced autophagy in melanoma.
Moller, K., Sigurbjornsdottir, S., Arnthorsson, A.O., Pogenberg, V., Dilshat, R., Fock, V., Brynjolfsdottir, S.H., Bindesboll, C., Bessadottir, M., Ogmundsdottir, H.M., Simonsen, A., Larue, L., Wilmanns, M., Thorsson, V., Steingrimsson, E., Ogmundsdottir, M.H.
Sci Rep