CATH Classification

Domain Context

CATH Clusters

Superfamily FAD/NAD(P)-binding domain
Functional Family Thioredoxin reductase 1, cytoplasmic

Enzyme Information

UniProtKB Entries (1)

G4V8J4
G4V8J4_SCHMA
Schistosoma mansoni
Thioredoxin glutathione reductase

PDB Structure

PDB 6FP4
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Fragment-Based Discovery of a Regulatory Site in Thioredoxin Glutathione Reductase Acting as "Doorstop" for NADPH Entry.
Silvestri, I., Lyu, H., Fata, F., Boumis, G., Miele, A.E., Ardini, M., Ippoliti, R., Bellelli, A., Jadhav, A., Lea, W.A., Simeonov, A., Cheng, Q., Arner, E.S.J., Thatcher, G.R.J., Petukhov, P.A., Williams, D.L., Angelucci, F.
ACS Chem. Biol.