CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.357 | Tetracycline Repressor; domain 2 |
|
1.10.357.90 | Telomerase reverse transcriptase (TERT), thumb domain |
Domain Context
CATH Clusters
| Superfamily | 1.10.357.90 |
| Functional Family | Telomerase reverse transcriptase |
Enzyme Information
UniProtKB Entries (0)
PDB Structure
| PDB | 6E53 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
A non-natural nucleotide uses a specific pocket to selectively inhibit telomerase activity.
Plos Biol.
|