CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.10 | Roll |
|
3.10.20 | Ubiquitin-like (UB roll) |
|
3.10.20.90 | Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 |
Domain Context
CATH Clusters
| Superfamily | Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 |
| Functional Family | Merlin isoform 2 |
Enzyme Information
UniProtKB Entries (1)
| P35240 |
MERL_HUMAN
Homo sapiens
Merlin
|
PDB Structure
| PDB | 6CDS |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Lipid binding promotes the open conformation and tumor-suppressive activity of neurofibromin 2.
Nat Commun
|