CATH Classification

Domain Context

CATH Clusters

Superfamily Jelly Rolls
Functional Family

Enzyme Information

1.13.11.6
3-hydroxyanthranilate 3,4-dioxygenase.
based on mapping to UniProt Q1LCS4
3-hydroxyanthranilate + O(2) = 2-amino-3-carboxymuconate semialdehyde.
-!- The product of the reaction spontaneously rearrange to quinolinic acid (quin). -!- Formerly EC 1.13.1.6.

UniProtKB Entries (1)

Q1LCS4
3HAO_CUPMC
Cupriavidus metallidurans CH34
3-hydroxyanthranilate 3,4-dioxygenase

PDB Structure

PDB 6BVQ
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Adapting to oxygen: 3-Hydroxyanthrinilate 3,4-dioxygenase employs loop dynamics to accommodate two substrates with disparate polarities.
Yang, Y., Liu, F., Liu, A.
J. Biol. Chem.