CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.390 | Collagenase (Catalytic Domain) |
|
3.40.390.10 | Collagenase (Catalytic Domain) |
Domain Context
CATH Clusters
| Superfamily | Collagenase (Catalytic Domain) |
| Functional Family |
Enzyme Information
| 3.4.24.19 |
Procollagen C-endopeptidase.
based on mapping to UniProt P13497
Cleavage of the C-terminal propeptide at Ala-|-Asp in type I and II procollagens and at Arg-|-Asp in type III.
-!- The activity is increased by calcium and by an enhancer glycoprotein.
|
UniProtKB Entries (1)
| P13497 |
BMP1_HUMAN
Homo sapiens
Bone morphogenetic protein 1
|
PDB Structure
| PDB | 6BTQ |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Reverse Hydroxamate Inhibitors of Bone Morphogenetic Protein 1.
ACS Med Chem Lett
|