CATH Classification

Domain Context

CATH Clusters

Superfamily Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1
Functional Family Talin 2

Enzyme Information

UniProtKB Entries (2)

P26039
TLN1_MOUSE
Mus musculus
Talin-1
P61224
RAP1B_HUMAN
Homo sapiens
Ras-related protein Rap-1b

PDB Structure

PDB 6BA6
External Links
Method SOLUTION NMR
Organism
Primary Citation
Structure of Rap1b bound to talin reveals a pathway for triggering integrin activation.
Zhu, L., Yang, J., Bromberger, T., Holly, A., Lu, F., Liu, H., Sun, K., Klapproth, S., Hirbawi, J., Byzova, T.V., Plow, E.F., Moser, M., Qin, J.
Nat Commun