1 keywords

CATH Domain 6b5kB00

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.90 Alpha-Beta Complex
Topology 3.90.550 Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A
Homologous Superfamily 3.90.550.10 Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A

Domain Context

CATH Clusters

Superfamily Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A
Functional Family Glucose-1-phosphate thymidylyltransferase

Enzyme Information

2.7.7.24
Glucose-1-phosphate thymidylyltransferase.
based on mapping to UniProt P9WH13
dTTP + alpha-D-glucose 1-phosphate = diphosphate + dTDP-alpha-D-glucose.

UniProtKB Entries (1)

P9WH13
RMLA_MYCTU
Mycobacterium tuberculosis H37Rv
Glucose-1-phosphate thymidylyltransferase

PDB Structure

PDB 6B5K
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The structure of glucose-1-phosphate thymidylyltransferase from Mycobacterium tuberculosis reveals the location of an essential magnesium ion in the RmlA-type enzymes.
Brown, H.A., Thoden, J.B., Tipton, P.A., Holden, H.M.
Protein Sci.