CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.20 | Alpha-Beta Barrel |
|
3.20.20 | TIM Barrel |
|
3.20.20.140 | Metal-dependent hydrolases |
Domain Context
CATH Clusters
| Superfamily | Metal-dependent hydrolases |
| Functional Family | Dihydropyrimidinase like 3 |
Enzyme Information
| 3.5.2.2 |
Dihydropyrimidinase.
based on mapping to UniProt Q9I676
5,6-dihydrouracil + H(2)O = 3-ureidopropanoate.
-!- Also acts on dihydrothymine and hydantoin.
|
UniProtKB Entries (1)
| Q9I676 |
HYDA_PSEAE
Pseudomonas aeruginosa PAO1
D-hydantoinase/dihydropyrimidinase
|
PDB Structure
| PDB | 6AJD |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal structures of monometallic dihydropyrimidinase and the human dihydroorotase domain K1556A mutant reveal no lysine carbamylation within the active site
Biochem. Biophys. Res. Commun.
|
