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1 keywords

CATH Domain 5zhlA02

CATH Classification

Level CATH Code Description
Class 1 Mainly Alpha
Architecture 1.10 Orthogonal Bundle
Topology 1.10.1270 Trp Operon Repressor; Chain A
Homologous Superfamily 1.10.1270.20 tRNA(m1g37)methyltransferase, domain 2

Domain Context

CATH Clusters

Superfamily tRNA(m1g37)methyltransferase, domain 2
Functional Family tRNA (guanine-N(1)-)-methyltransferase

Enzyme Information

UniProtKB Entries (0)

PDB Structure

PDB 5ZHL
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Thienopyrimidinone Derivatives That Inhibit Bacterial tRNA (Guanine37-N1)-Methyltransferase (TrmD) by Restructuring the Active Site with a Tyrosine-Flipping Mechanism.
Zhong, W., Pasunooti, K.K., Balamkundu, S., Wong, Y.H., Nah, Q., Gadi, V., Gnanakalai, S., Chionh, Y.H., McBee, M.E., Gopal, P., Lim, S.H., Olivier, N., Buurman, E.T., Dick, T., Liu, C.F., Lescar, J., Dedon, P.C.
J.Med.Chem.
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