CATH Domain 5yl2A02

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.1330	60s Ribosomal Protein L30; Chain: A;
	3.30.1330.20	Tubulin/FtsZ, C-terminal domain

Superfamily	Tubulin/FtsZ, C-terminal domain
Functional Family

P63043	STMN4_RAT Rattus norvegicus Stathmin-4
E1BQ43	E1BQ43_CHICK Gallus gallus Uncharacterized protein
P02554	TBB_PIG Sus scrofa Tubulin beta chain

PDB	5YL2
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	The compound millepachine and its derivatives inhibit tubulin polymerization by irreversibly binding to the colchicine-binding site in beta-tubulin. Jianhong, Y., Wei, Y., Yamei, Y., Yuxi, W., Tao, Y., Linlin, X., Xue, Y., Caofeng, L., Zuowei, L., Xiaoxin, C., Mengshi, H., Li, Z., Qiang, Q., Heying, P., Dan, L., Fang, W., Peng, B., Jiaolin, W., Haoyu, Y., Lijuan, C. J. Biol. Chem.