×

Network disruptions

We have been experiencing disruptions on our local network which has affected the stability of these web pages. We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.

CATH Classification

Domain Context

CATH Clusters

Superfamily 2.20.28.200
Functional Family NAD-dependent protein deacetylase sirtuin-6

Enzyme Information

3.5.1.-
In linear amides.
based on mapping to UniProt Q8N6T7

UniProtKB Entries (1)

P68431
H31_HUMAN
Homo sapiens
Histone H3.1

PDB Structure

PDB 5Y2F
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Identification of a cellularly active SIRT6 allosteric activator.
Huang, Z., Zhao, J., Deng, W., Chen, Y., Shang, J., Song, K., Zhang, L., Wang, C., Lu, S., Yang, X., He, B., Min, J., Hu, H., Tan, M., Xu, J., Zhang, Q., Zhong, J., Sun, X., Mao, Z., Lin, H., Xiao, M., Chin, Y.E., Jiang, H., Xu, Y., Chen, G., Zhang, J.
Nat. Chem. Biol.
CATH-Gene3D is a Global Biodata Core Resource Learn more...