CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.50.970
Functional Family Transketolase

Enzyme Information

2.2.1.1
Transketolase.
based on mapping to UniProt P34736
Sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-ribose 5-phosphate + D-xylulose 5-phosphate.
-!- Wide specificity for both reactants, e.g. converts hydroxypyruvate and R-CHO into CO(2) and R-CHOH-CO-CH(2)OH. -!- The enzyme from the bacterium Alcaligenes faecalis shows high activity with D-erythrose 4-phosphate as acceptor.

UniProtKB Entries (1)

P34736
TKT_PICST
Scheffersomyces stipitis CBS 6054
Transketolase

PDB Structure

PDB 5XRY
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The Mesomeric Effect of Thiazolium on non-Kekule Diradicals in Pichia stipitis Transketolase.
Hsu, N.S., Wang, Y.L., Lin, K.H., Chang, C.F., Lyu, S.Y., Hsu, L.J., Liu, Y.C., Chang, C.Y., Wu, C.J., Li, T.L.
Angew. Chem. Int. Ed. Engl.