CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.50.970
Functional Family Transketolase

Enzyme Information

2.2.1.1
Transketolase.
based on mapping to UniProt P34736
Sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-ribose 5-phosphate + D-xylulose 5-phosphate.
-!- Wide specificity for both reactants, e.g. converts hydroxypyruvate and R-CHO into CO(2) and R-CHOH-CO-CH(2)OH. -!- The enzyme from the bacterium Alcaligenes faecalis shows high activity with D-erythrose 4-phosphate as acceptor.

UniProtKB Entries (1)

P34736
TKT_PICST
Scheffersomyces stipitis CBS 6054
Transketolase

PDB Structure

PDB 5XPS
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Evidence of Diradicals Involved in the Yeast Transketolase Catalyzed Keto-Transferring Reactions.
Hsu, N.S., Wang, Y.L., Lin, K.H., Chang, C.F., Ke, S.C., Lyu, S.Y., Hsu, L.J., Li, Y.S., Chen, S.C., Wang, K.C., Li, T.L.
Chembiochem