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CATH Classification

Domain Context

CATH Clusters

Superfamily Helix hairpin bin
Functional Family Tubulin beta chain

Enzyme Information

UniProtKB Entries (3)

Q2XVP4
TBA1B_PIG
Sus scrofa
Tubulin alpha-1B chain
E1BQ43
E1BQ43_CHICK
Gallus gallus
Uncharacterized protein
P63043
STMN4_RAT
Rattus norvegicus
Stathmin-4

PDB Structure

PDB 5XP3
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The compound millepachine and its derivatives inhibit tubulin polymerization by irreversibly binding to the colchicine-binding site in beta-tubulin.
Jianhong, Y., Wei, Y., Yamei, Y., Yuxi, W., Tao, Y., Linlin, X., Xue, Y., Caofeng, L., Zuowei, L., Xiaoxin, C., Mengshi, H., Li, Z., Qiang, Q., Heying, P., Dan, L., Fang, W., Peng, B., Jiaolin, W., Haoyu, Y., Lijuan, C.
J. Biol. Chem.
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