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1 keywords

CATH Domain 5x8qA00

CATH Classification

Level CATH Code Description
Class 1 Mainly Alpha
Architecture 1.10 Orthogonal Bundle
Topology 1.10.565 Retinoid X Receptor
Homologous Superfamily 1.10.565.10 Retinoid X Receptor

Domain Context

CATH Clusters

Superfamily Retinoid X Receptor
Functional Family Nuclear orphan receptor ROR-beta

Enzyme Information

UniProtKB Entries (1)

Q9Y618
NCOR2_HUMAN
Homo sapiens
Nuclear receptor corepressor 2

PDB Structure

PDB 5X8Q
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Ternary complex of human ROR gamma ligand-binding domain, inverse agonist and SMRT peptide shows a unique mechanism of corepressor recruitment
Noguchi, M., Nomura, A., Murase, K., Doi, S., Yamaguchi, K., Hirata, K., Shiozaki, M., Hirashima, S., Kotoku, M., Yamaguchi, T., Katsuda, Y., Steensma, R., Li, X., Tao, H., Tse, B., Fenn, M., Babine, R., Bradley, E., Crowe, P., Thacher, S., Adachi, T., Kamada, M.
Genes Cells
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