CATH Classification

Domain Context

CATH Clusters

Superfamily HUPs
Functional Family

Enzyme Information

2.7.7.3
Pantetheine-phosphate adenylyltransferase.
based on mapping to UniProt Q9I6D1
ATP + pantetheine 4'-phosphate = diphosphate + 3'-dephospho-CoA.
-!- The enzyme from several bacteria (e.g. Escherichia coli, Bacillus subtilis and Haemophilus influenzae) has been shown to be bifunctional and also to possess the activity of EC 2.3.1.157.

UniProtKB Entries (1)

Q9I6D1
COAD_PSEAE
Pseudomonas aeruginosa PAO1
Phosphopantetheine adenylyltransferase

PDB Structure

PDB 5X6F
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Umbrella Sampling and X-ray Crystallographic Analysis Unveil an Arg-Asp Gate Facilitating Inhibitor Binding Inside Phosphopantetheine Adenylyltransferase Allosteric Cleft.
Mondal, A., Chatterjee, R., Datta, S.
J Phys Chem B