CATH Classification

Domain Context

CATH Clusters

Superfamily Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1
Functional Family Microtubule-associated proteins 1A/1B light chain 3B

Enzyme Information

UniProtKB Entries (2)

Q0PF16
TRIM5_MACMU
Macaca mulatta
Tripartite motif-containing protein 5
Q9GZQ8
MLP3B_HUMAN
Homo sapiens
Microtubule-associated proteins 1A/1B light chain 3B

PDB Structure

PDB 5W9A
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
A helical LC3-interacting region mediates the interaction between the retroviral restriction factor Trim5 alpha and mammalian autophagy-related ATG8 proteins.
Keown, J.R., Black, M.M., Ferron, A., Yap, M., Barnett, M.J., Pearce, F.G., Stoye, J.P., Goldstone, D.C.
J. Biol. Chem.