CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.10 | Roll |
|
3.10.20 | Ubiquitin-like (UB roll) |
|
3.10.20.90 | Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 |
Domain Context
CATH Clusters
| Superfamily | Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 |
| Functional Family | Microtubule-associated proteins 1A/1B light chain 3B |
Enzyme Information
UniProtKB Entries (2)
| Q0PF16 |
TRIM5_MACMU
Macaca mulatta
Tripartite motif-containing protein 5
|
| Q9GZQ8 |
MLP3B_HUMAN
Homo sapiens
Microtubule-associated proteins 1A/1B light chain 3B
|
PDB Structure
| PDB | 5W9A |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
A helical LC3-interacting region mediates the interaction between the retroviral restriction factor Trim5 alpha and mammalian autophagy-related ATG8 proteins.
J. Biol. Chem.
|
