CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.640 | Aspartate Aminotransferase; domain 2 |
|
3.40.640.10 | Type I PLP-dependent aspartate aminotransferase-like (Major domain) |
Domain Context
CATH Clusters
| Superfamily | Type I PLP-dependent aspartate aminotransferase-like (Major domain) |
| Functional Family |
Enzyme Information
| 2.6.1.101 |
L-glutamine:3-amino-2,3-dideoxy-scyllo-inosose aminotransferase.
based on mapping to UniProt Q4R0W2
L-glutamine + 3-amino-2,3-dideoxy-scyllo-inosose = 2-oxoglutaramate + 2-deoxystreptamine.
-!- Involved in the biosynthetic pathways of several clinically important aminocyclitol antibiotics, including kanamycin, butirosin, neomycin and ribostamycin. -!- Also catalyzes EC 2.6.1.100.
|
| 2.6.1.100 |
L-glutamine:2-deoxy-scyllo-inosose aminotransferase.
based on mapping to UniProt Q4R0W2
L-glutamine + 2-deoxy-scyllo-inosose = 2-oxoglutaramate + 2-deoxy-scyllo- inosamine.
-!- Involved in the biosynthetic pathways of several clinically important aminocyclitol antibiotics, including kanamycin, butirosin, neomycin and ribostamycin. -!- Also catalyzes EC 2.6.1.101.
|
UniProtKB Entries (1)
| Q4R0W2 |
GLDSA_STRRI
Streptomyces ribosidificus
L-glutamine:2-deoxy-scyllo-inosose aminotransferase
|
PDB Structure
| PDB | 5W70 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
The structure of RbmB from Streptomyces ribosidificus, an aminotransferase involved in the biosynthesis of ribostamycin.
Protein Sci.
|
