CATH Classification

Domain Context

CATH Clusters

Superfamily 5' to 3' exonuclease, C-terminal subdomain
Functional Family DNA polymerase lambda

Enzyme Information

2.7.7.7
DNA-directed DNA polymerase.
based on mapping to UniProt Q9NP87
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
-!- Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. -!- Cannot initiate a chain de novo. -!- Requires a primer which may be DNA or RNA. -!- See also EC 2.7.7.49.

UniProtKB Entries (1)

Q9NP87
DPOLM_HUMAN
Homo sapiens
DNA-directed DNA/RNA polymerase mu

PDB Structure

PDB 5VZH
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural accommodation of ribonucleotide incorporation by the DNA repair enzyme polymerase Mu.
Moon, A.F., Pryor, J.M., Ramsden, D.A., Kunkel, T.A., Bebenek, K., Pedersen, L.C.
Nucleic Acids Res.