CATH Domain 5uqwB00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.300	P-loop containing nucleotide triphosphate hydrolases

Domain Context

CATH Clusters

Superfamily	P-loop containing nucleotide triphosphate hydrolases
Functional Family	KRAS proto-oncogene, GTPase

Enzyme Information

UniProtKB Entries (1)

RASK_HUMAN

Homo sapiens

GTPase KRas

PDB Structure

PDB	5UQW
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Multivalent Small-Molecule Pan-RAS Inhibitors. Welsch, M.E., Kaplan, A., Chambers, J.M., Stokes, M.E., Bos, P.H., Zask, A., Zhang, Y., Sanchez-Martin, M., Badgley, M.A., Huang, C.S., Tran, T.H., Akkiraju, H., Brown, L.M., Nandakumar, R., Cremers, S., Yang, W.S., Tong, L., Olive, K.P., Ferrando, A., Stockwell, B.R. Cell