×

Network disruptions

We have been experiencing disruptions on our local network which has affected the stability of these web pages. We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.

1 keywords

CATH Domain 5u7eA00

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.90 Alpha-Beta Complex
Topology 3.90.79 Nucleoside Triphosphate Pyrophosphohydrolase
Homologous Superfamily 3.90.79.10 Nucleoside Triphosphate Pyrophosphohydrolase

Domain Context

CATH Clusters

Superfamily Nucleoside Triphosphate Pyrophosphohydrolase
Functional Family Dihydroneopterin triphosphate pyrophosphatase

Enzyme Information

3.6.1.67
Dihydroneopterin triphosphate diphosphatase.
based on mapping to UniProt P0AFC1
7,8-dihydroneopterin 3'-triphosphate + H(2)O = 7,8-dihydroneopterin 3'-phosphate + diphosphate.
-!- The enzyme participates in a folate biosynthesis pathway, which is found in bacteria, fungi, and plants. -!- Formerly EC 3.6.1.n4.

UniProtKB Entries (1)

P0AFC1
NUDB_ECO57
Escherichia coli O157:H7
Dihydroneopterin triphosphate diphosphatase

PDB Structure

PDB 5U7E
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Metal ion coordination in the E. coli Nudix hydrolase dihydroneopterin triphosphate pyrophosphatase: New clues into catalytic mechanism.
Hill, S.E., Nguyen, E., Ukachukwu, C.U., Freeman, D.M., Quirk, S., Lieberman, R.L.
PLoS ONE
CATH-Gene3D is a Global Biodata Core Resource Learn more...