CATH Domain 5u36A02

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.240	Tyrosyl-Transfer RNA Synthetase
	1.10.240.10	Tyrosyl-Transfer RNA Synthetase

Domain Context

CATH Clusters

Superfamily	Tyrosyl-Transfer RNA Synthetase
Functional Family

Enzyme Information

6.1.1.1

Tyrosine--tRNA ligase.

based on mapping to UniProt Q57834

ATP + L-tyrosine + tRNA(Tyr) = AMP + diphosphate + L-tyrosyl-tRNA(Tyr).

UniProtKB Entries (1)

SYY_METJA

Methanocaldococcus jannaschii DSM 2661

Tyrosine--tRNA ligase

PDB Structure

PDB	5U36
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Genetically encoding phosphotyrosine and its nonhydrolyzable analog in bacteria. Luo, X., Fu, G., Wang, R.E., Zhu, X., Zambaldo, C., Liu, R., Liu, T., Lyu, X., Du, J., Xuan, W., Yao, A., Reed, S.A., Kang, M., Zhang, Y., Guo, H., Huang, C., Yang, P.Y., Wilson, I.A., Schultz, P.G., Wang, F. Nat. Chem. Biol.