CATH Domain 5ti6A01

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CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.20	Up-down Bundle
	1.20.920	Histone Acetyltransferase; Chain A
	1.20.920.10	Bromodomain-like

Domain Context

CATH Clusters

Superfamily	Bromodomain-like
Functional Family	Bromodomain-containing protein 4

Enzyme Information

UniProtKB Entries (1)

BRD4_HUMAN

Homo sapiens

Bromodomain-containing protein 4

PDB Structure

PDB	5TI6
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Identification of a Novel Class of BRD4 Inhibitors by Computational Screening and Binding Simulations. Allen, B.K., Mehta, S., Ember, S.W.J., Zhu, J.Y., Schonbrunn, E., Ayad, N.G., Schurer, S.C. ACS Omega