CATH Classification

Domain Context

CATH Clusters

Superfamily Mannose-Binding Protein A, subunit A
Functional Family Snaclec rhodocetin subunit delta

Enzyme Information

UniProtKB Entries (2)

P17301
ITA2_HUMAN
Homo sapiens
Integrin alpha-2
D2YW39
SLEC_CALRH
Calloselasma rhodostoma
Snaclec rhodocetin subunit gamma

PDB Structure

PDB 5THP
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Dramatic and concerted conformational changes enable rhodocetin to block alpha 2 beta 1 integrin selectively.
Eble, J.A., McDougall, M., Orriss, G.L., Niland, S., Johanningmeier, B., Pohlentz, G., Meier, M., Karrasch, S., Estevao-Costa, M.I., Martins Lima, A., Stetefeld, J.
PLoS Biol.