CATH Classification

Domain Context

CATH Clusters

Superfamily Succinyl-CoA synthetase domains
Functional Family ATP-citrate synthase subunit

Enzyme Information

2.3.3.8
ATP citrate synthase.
based on mapping to UniProt P53396
ADP + phosphate + acetyl-CoA + oxaloacetate = ATP + citrate + CoA.
-!- The enzyme can be dissociated into components, two of which are identical with EC 4.1.3.34 and EC 6.2.1.18. -!- Formerly EC 4.1.3.8.

UniProtKB Entries (1)

P53396
ACLY_HUMAN
Homo sapiens
ATP-citrate synthase

PDB Structure

PDB 5TDF
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Binding of hydroxycitrate to human ATP-citrate lyase.
Hu, J., Komakula, A., Fraser, M.E.
Acta Crystallogr D Struct Biol