CATH Classification

Domain Context

CATH Clusters

Superfamily Fructose-1,6-Bisphosphatase, subunit A, domain 1
Functional Family Fructose-1,6-bisphosphatase isozyme 2

Enzyme Information

3.1.3.11
Fructose-bisphosphatase.
based on mapping to UniProt O00757
D-fructose 1,6-bisphosphate + H(2)O = D-fructose 6-phosphate + phosphate.
-!- The animal enzyme also acts on sedoheptulose 1,7-bisphosphate.

UniProtKB Entries (1)

O00757
F16P2_HUMAN
Homo sapiens
Fructose-1,6-bisphosphatase isozyme 2

PDB Structure

PDB 5Q0C
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Human liver fructose-1,6-bisphosphatase 1 (fructose 1,6-bisphosphate 1-phosphatase, E.C.3.1.3.11) complexed with the allosteric inhibitor 1-(5-bromo-1,3-thiazol-2-yl)-3-[5-(4-methoxyphenyl)thiophen-2-yl]sulfonylurea and with f2,6p
Ruf, A., Joseph, C., Alker, A., Banner, D., Tetaz, T., Benz, J., Kuhn, B., Rudolph, M.G.
To be published