CATH Classification

Domain Context

CATH Clusters

Superfamily Putative phosphatase; domain 2
Functional Family Beta-phosphoglucomutase

Enzyme Information

5.4.2.6
Beta-phosphoglucomutase.
based on mapping to UniProt P71447
Beta-D-glucose 1-phosphate = beta-D-glucose 6-phosphate.
-!- The enzyme is able to autophosphorylate itself with its substrate beta-D-glucose 1-phosphate. -!- Although this is a slow reaction, only a single turnover is required for activation. -!- Once the phosphorylated enzyme is formed, it generates the reaction intermediate beta-D-glucose 1,6-bisphosphate, which can be used to phosphorylate the enzyme in subsequent cycles. -!- Cf. EC 5.4.2.2.

UniProtKB Entries (1)

P71447
PGMB_LACLA
Lactococcus lactis subsp. lactis Il1403
Beta-phosphoglucomutase

PDB Structure

PDB 5OLX
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Observing enzyme ternary transition state analogue complexes by19F NMR spectroscopy.
Ampaw, A., Carroll, M., von Velsen, J., Bhattasali, D., Cohen, A., Bowler, M.W., Jakeman, D.L.
Chem Sci